EPT Fumarate (N-ethyl-N-propyltryptamine) Product Description

Introduction

EPT fumarate is the fumaric acid salt form of N-ethyl-N-propyltryptamine (EPT), a synthetic tryptamine-class compound. EPT is a rare psychoactive tryptamine structurally related to classical substances like DMT and MET. This fumarate salt aids in stabilizing the compound and improving its water solubility, making it suitable for research applications. EPT fumarate appears typically as a white to off-white crystalline powder, used strictly for biochemical and pharmacological research rather than human consumption.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Formula: C15H22N2·C4H4O4 (EPT fumarate)

• Molecular Weight: Approximately 294.3 g/mol (salt form)

• CAS Number: 850032-68-7

• IUPAC Name: 3-[2-(ethyl(propyl)amino)ethyl]-1H-indole fumarate

• Synonyms: EPT fumarate, N-ethyl-N-propyltryptamine fumarate, Ethylpropyltryptamine fumarate

2.2 Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder

• Purity: Typically ≥97% in research-grade materials

• Solubility: Enhanced aqueous solubility due to fumarate salt; soluble in ethanol, methanol, and other organic solvents

• Storage Recommendations: Store sealed in a cool, dry place protected from light and moisture; best kept at room temperature or cooler to maintain chemical integrity

Pharmacological Profile and Mechanism of Action

3.1 Proposed Mechanism of Action

EPT acts as a serotonin receptor agonist, particularly targeting 5-HT2A receptors, which mediate psychedelic and hallucinogenic effects in experimental models. The fumarate salt itself does not alter pharmacodynamics but improves compound stability and bioavailability in research settings.

3.2 Research Applications

EPT fumarate is employed in research studies exploring serotonergic pathways, receptor binding profiles, and structure-activity relationships within tryptamine psychedelics. Its availability in fumarate salt form allows precise dosing and improved experimental reproducibility in biochemical and neuroscience studies.

Comparative Analysis with Related Compounds

4.1 Comparison with Related Compounds

EPT fumarate is structurally and pharmacologically related to other tryptamines such as DMT, MET, and DET, differing mainly in its alkyl substitutions affecting receptor affinity and metabolism. The fumarate salt improves upon the freebase form by offering enhanced solubility and stability, which are critical for laboratory-based research protocols.

4.2 Advantages for Research

The salt form’s improved solubility facilitates formulation for in vitro and in vivo assays. The stable crystalline powder form supports accurate quantification and dosing. EPT fumarate’s unique substitution pattern provides research opportunities into novel psychedelic activity and serotonergic receptor interactions.

Safety and Handling Guidelines

5.1 Laboratory Safety

Handle using standard personal protective equipment including gloves, lab coat, and eye protection. Use in well-ventilated areas or fume hoods to prevent inhalation. Avoid direct skin or eye contact.

5.2 Disposal and Environmental Considerations

Dispose according to hazardous chemical waste regulations. Prevent environmental contamination by following institutional waste disposal protocols.

5.3 Regulatory Status

EPT fumarate is a research chemical, not approved for human consumption or therapeutic use. Its regulatory status varies by jurisdiction; compliance with all relevant legal and institutional requirements is mandatory.

Frequently Asked Questions (FAQs)

1. What is the chemical formula of EPT fumarate?
   C15H22N2·C4H4O4.

2. What is the CAS number for EPT fumarate?
   850032-68-7.

3. Is EPT fumarate soluble in water?
   Yes, the fumarate salt enhances water solubility compared to freebase form.

4. Which receptors does EPT primarily target?
   Serotonin 5-HT2A receptors.

5. What research purposes does EPT fumarate serve?
   Serotonergic receptor studies, psychedelic pharmacology, and structure-activity relationship investigations.

Conclusion

EPT fumarate is a stable, water-soluble salt form of N-ethyl-N-propyltryptamine designed for research into serotonergic psychedelics. Its improved solubility and crystalline powder form support precise experimental use in pharmacological and neurochemical studies.