DeschloroEtizolam 5 mg Pellets

PRODUCT DESCRIPTION

Introduction

DeschloroEtizolam 5 mg pellets are a potent research chemical form of deschloroetizolam, a thienotriazolodiazepine closely related to etizolam. This compound exhibits strong anxiolytic, sedative, muscle relaxant, hypnotic, anticonvulsant, and amnesic properties by modulating the GABA-A receptor in the central nervous system. The 5 mg pellet dosage provides precise, high-concentration doses ideal for pharmacological, neurochemical, and toxicological research under controlled experimental conditions.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: 2-Ethyl-9-methyl-4-phenyl-6H-thieno[3,2-f]triazolo[4,3-a]diazepine

• Chemical Formula: C17H16N4S

• Molecular Weight: 308.4 g/mol

• CAS Number: 40054-73-7

• Synonyms:

  • Deschloroetizolam

  • Thienotriazolodiazepine

2.2 Physical Properties and Purity Standards

• Appearance: Solid white crystalline pellets

• Dosage Strength: 5 mg deschloroetizolam per pellet

• Purity: ≥ 99% purity pharmaceutical/research grade

• Solubility: Soluble in DMSO, dimethylformamide, partially soluble in aqueous buffers

• Storage Recommendations: Store in a cool, dark, dry place; refrigeration at 2-8°C recommended to preserve potency

Pharmacological Profile and Mechanism of Action

3.1 Mechanism of Action

Deschloroetizolam works as a positive allosteric modulator of GABA-A receptors, enhancing the inhibitory effects of GABA in the CNS. This leads to depressant, anxiolytic, sedative, muscle relaxant, and hypnotic effects. It is considered approximately twice as potent as alprazolam per mg.

3.2 Research Applications

Primarily used for researching benzodiazepine receptor binding, CNS depressant effects, anxiolysis, and muscle relaxation in experimental and pharmacokinetic studies. The pellet form enables accurate dosing in behavioral and toxicology assays.

Comparative Analysis with Related Compounds

4.1 Compared to Etizolam and Alprazolam

Deschloroetizolam is structurally similar to etizolam but differs by the absence of a chlorine atom, influencing potency and receptor binding. It exhibits higher potency than alprazolam and longer duration of action than etizolam.

4.2 Advantages for Research

Stable pellet form with highly pure active ingredients supports precise dosing and ease of handling. Suitable for long-term storage and consistent experimental results.

Safety and Handling Guidelines

5.1 Laboratory Safety

Wear gloves and eye protection during handling. Use in well-ventilated areas. Avoid inhalation and skin contact.

5.2 Disposal

Dispose of unused material according to hazardous chemical waste regulations.

5.3 Regulatory Status

Deschloroetizolam is regulated or controlled in many jurisdictions due to potency and abuse potential. Verify compliance with regional regulations before use.

Frequently Asked Questions (FAQs)

1. What is Deschloroetizolam?
   A potent thienotriazolodiazepine research chemical similar to etizolam.

2. What is the dosage per pellet?
   5 mg per pellet.

3. What effects does it produce?
   Anxiolytic, sedative, muscle relaxant, hypnotic, and amnesic effects.

4. Is the compound soluble in water?
   Partially soluble, more soluble in DMSO and organic solvents.

5. Is it regulated?
   Yes, regulated under controlled substances in many countries.

Conclusion

Deschloroetizolam 5 mg pellets offer a high-purity, potent benzodiazepine analog ideal for advanced neuropharmacological research. Their pellet form ensures reliable dosing and stability for experimental consistency, with necessary compliance to safety and regulatory measures.