Chem-mist 4F-MPH Spray 10%

PRODUCT DESCRIPTION

Introduction

Chem-mist 4F-MPH Spray 10% is a liquid formulation of 4-Fluoromethylphenidate (4F-MPH), a fluorinated analog of methylphenidate known for its potent stimulant effects. This 10% solution is designed for efficient sublingual or buccal delivery, allowing precise dosing suitable for research into stimulant pharmacodynamics, receptor binding, and behavioral effects. The product is manufactured with a vanilla aroma to enhance user experience during administration.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: 4-Fluoromethylphenidate

• Molecular Formula: C14H18FNO2

• Molecular Weight: 251.3 g/mol

• CAS Number: 1354631-33-6

• IUPAC Name: methyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate

• Synonyms:

  • 4F-MPH

  • 4-Fluoromethylphenidate

  • 4FMPH

2.2 Physical Properties and Purity Standards

• Appearance: Clear to light yellow liquid

• Concentration: 10% w/v (100 mg/mL)

• Purity: ≥98% pharmaceutical grade purity

• Solubility: Soluble in water and organic solvents such as distillate polyglycols (E1520); stabilized by additives including emulsifiers, food dye, and aroma agents

• Storage Recommendations: Store sealed in amber glass vials at 4°C to -20°C, away from light and moisture

Pharmacological Profile and Mechanism of Action

3.1 Mechanism of Action

4F-MPH acts as a dopamine and norepinephrine reuptake inhibitor, increasing synaptic concentrations of these neurotransmitters, resulting in stimulant and euphoric effects. The fluorine substitution may alter binding affinity and metabolic resistance compared to methylphenidate.

3.2 Research Applications

Used in pharmacological and neurochemical research to study stimulant effects on monoamine systems, behavioral models of attention and alertness, and toxicological profiles. Spray delivery enables precise dosing for in vitro and in vivo experimental use.

Comparative Analysis with Related Compounds

4.1 Compare the compound to Compound(s) often compared to

4F-MPH is structurally related to methylphenidate but with a fluorine substitution at the para-position on the phenyl ring, enhancing potency in some assays. Unlike classical methylphenidate salts, 4F-MPH may exhibit differing pharmacokinetics and potency in human subjects.

4.2 Advantages for Research

Spray form ensures ease of dosing and rapid absorption in sublingual administration. The 10% solution balances concentration and manageability for versatile dosing ranges.

Safety and Handling Guidelines

5.1 Laboratory Safety

Use protective gloves, eyewear, and lab coats. Handle in well-ventilated rooms or fume hoods. Avoid skin exposure and inhalation.

5.2 Disposal and Environmental Considerations

Follow controlled chemical waste disposal protocols. Avoid environmental contamination.

5.3 Regulatory Status

4F-MPH is regulated or considered a controlled research chemical in many areas. Local legal compliance is essential.

Frequently Asked Questions (FAQs)

1. What is the concentration of Chem-mist 4F-MPH spray?
   10% w/v or 100 mg/mL.

2. What is 4F-MPH’s mechanism of action?
   Dopamine and norepinephrine reuptake inhibition stimulant.

3. What solvents and additives are in the formulation?
   Water, polyglycol (E1520), emulsifiers, vanilla aroma, food dye.

4. What research areas use Chem-mist 4F-MPH spray?
   Neuropharmacology, behavioral studies, toxicology.

5. Is 4F-MPH regulated?
   Yes, check local laws before handling or research use.

Conclusion

Chem-mist 4F-MPH Spray 10% is a high-purity stimulant research chemical in an easy-to-use liquid spray form, optimized for sublingual delivery and advanced neurochemical studies with dose control and reproducibility.