Benzo Fury 6-APB 100mg Pellets

PRODUCT DESCRIPTION

Introduction

Benzo Fury, commonly known by its chemical name 6-APB (6-(2-aminopropyl)benzofuran), is an empathogenic psychoactive compound that belongs to the substituted benzofuran and phenethylamine classes. Presented here in 100mg pellet form, it is designed for research use, allowing precise dosage and ease of administration. Structurally, 6-APB is distinguished by its benzofuran ring, replacing the methylenedioxyphenyl group found in related substances such as MDA, imparting unique pharmacological effects that are partly serotonergic.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Formula: C11H13NO

• Molecular Weight: 175.23 g/mol

• CAS Number: 286834-85-3

• IUPAC Name: 1-(benzofuran-6-yl)propan-2-amine

• Synonyms:

  • 6-APB

  • Benzo Fury

  • Benzofuran 6-APB

  • 6-(2-Aminopropyl)benzofuran

2.2 Physical Properties and Purity Standards

• Appearance: White to off-white crystalline pellets

• Purity: ≥98% purity typical for research-grade material

• Solubility: Soluble in dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and ethanol at concentrations up to 20 mg/mL; moderately soluble in phosphate-buffered saline (pH 7.2) at approximately 1 mg/mL

• Storage Recommendations: Store at -20°C, sealed and protected from light and moisture to maintain compound integrity

Pharmacological Profile and Mechanism of Action

3.1 Proposed Mechanism of Action

6-APB functions as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It exhibits potent release of neurotransmitters serotonin, norepinephrine, and dopamine, leading to stimulant and empathogenic effects. Its action at serotonin receptor subtypes, especially 5-HT2C, contributes to its profile as an entactogen with psychoactive properties.

3.2 Research Applications

Used extensively in neuroscience and pharmacological research, 6-APB aids in the study of monoaminergic systems, receptor affinities, and psychoactive substance metabolism. Its pellet form and high purity enable precise dosing and robust reproducibility in in vitro and in vivo models. 6-APB is also instrumental in forensic science to understand designer drug profiles and toxicology.

Comparative Analysis with Related Compounds

4.1 Compare the compound to Compound(s) often compared to

6-APB shares chemical and pharmacological similarities with MDMA and other substituted phenethylamines but includes a benzofuran ring instead of methylenedioxy. Compared to 5-APB, its positional isomer, 6-APB may differ subtly in receptor binding and effect durations. Its empathogenic and stimulant effects are often compared with classic entactogens like MDA and MDMA but differ chemically and pharmacodynamically.

4.2 Advantages for Research

Its well-characterized receptor profile and defined molecular structure make 6-APB an excellent compound for studying structure-activity relationships within substituted benzofurans and phenethylamines. The pellet form ensures dosing accuracy and stability, an advantage over powder forms prone to variability.

Safety and Handling Guidelines

5.1 Laboratory Safety

Handle 6-APB pellets with gloves and appropriate PPE in a fume hood or well-ventilated lab. Avoid inhalation and direct skin contact. Use appropriate tools for pellet transfer and dosing.

5.2 Disposal and Environmental Considerations

Dispose of unused or contaminated material per institutional hazardous waste policies. Avoid environmental contamination and follow legal requirements for chemical waste disposal.

5.3 Regulatory Status

6-APB is regulated in various countries as a controlled substance or under analog laws due to its psychoactive effects. Verify the regulatory status locally before use.

Frequently Asked Questions (FAQs)

1. What is 6-APB?
   It is an empathogenic psychoactive compound known as Benzo Fury.

2. What are typical research uses?
   Neurotransmitter release studies, receptor binding assays, and forensic toxicology.

3. How soluble is 6-APB?
   Soluble at 20 mg/mL in DMF, DMSO, ethanol, and moderately in aqueous buffers.

4. What dosage form is supplied here?
   100mg crystalline pellets for precise dosing.

5. Is 6-APB legally restricted?
   It is controlled or regulated in many jurisdictions; confirm local laws.

Conclusion

Benzo Fury 6-APB 100mg pellets offer a high-purity, reliable form of this substituted benzofuran empathogen for detailed pharmacological and forensic research. Their chemical and pharmacodynamic properties support extensive monoaminergic and receptor interaction studies with strict adherence to safety and regulatory protocols.