2C-E Pellets 10 MG Product Description

Introduction

2C-E (2,5-Dimethoxy-4-ethylphenethylamine) is a synthetic psychedelic phenethylamine belonging to the 2C family of compounds, originally synthesized by Alexander Shulgin. It features methoxy groups at the 2 and 5 positions and an ethyl group at the 4 position on the phenyl ring. 2C-E is offered as 10 mg pellets for precise dosing in scientific research focused on psychedelic pharmacology and receptor dynamics. These pellets are intended strictly for laboratory research and do not carry any therapeutic or medical claims.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder formulated into 10 mg pellets.

• Purity: Typically ≥ 98%, verified by chromatographic and spectrometric analysis.

• Solubility: Soluble in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), with moderate water solubility (~5 mg/mL in PBS at pH 7.2).

• Storage Recommendations: Store pellets in airtight, light-resistant containers, in a cool, dry environment preferably refrigerated (2 to 8°C) to maintain chemical stability and potency.

Pharmacological Profile and Mechanism of Action

Proposed Mechanism of Action

2C-E primarily acts as a potent agonist at serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor subtypes, which mediate its psychedelic effects. These effects include alterations in perception, mood, cognition, and sensory processing. Unlike classic stimulants, 2C-E does not function primarily through monoamine reuptake inhibition or release but exerts effects through receptor activation. Its receptor binding profile is similar to other 2C family psychedelics, but the ethyl substitution at position 4 enhances potency and duration of action.

Research Applications

2C-E pellets are widely used in neuropharmacological research exploring serotonin receptor function, psychedelic behavioral effects, and receptor-ligand interaction studies. They enable accurate dose-response assessment and facilitate behavioral and pharmacokinetic studies in cellular, animal, and human models with reproducible results.

Comparative Analysis with Related Compounds

Comparison to 2C-B and other 2C Psychedelics

Compared to 2C-B (which has a bromine substitution at the 4 position), 2C-E features an ethyl group, leading to greater potency, longer duration, and more intense psychedelic experiences. While 2C-B is often viewed as more recreational, 2C-E is typically more potent and associated with deeper cognitive and perceptual alterations. It also differs from other 2C compounds like 2C-I and 2C-T-7, both structurally and in its longer-lasting effects.

Advantages for Research

• Allows precise control in dosing due to pellet formulation.

• Provides a unique pharmacological profile for studying serotonin receptor-mediated psychedelic mechanisms.

• Facilitates high-fidelity behavioral and pharmacokinetic experimentation.

Safety and Handling Guidelines

Laboratory Safety

Appropriate use of personal protective equipment (gloves, lab coat, eye protection) is essential. Conduct all handling in well-ventilated labs or fume hoods to mitigate inhalation or skin exposure risks. Due to pharmacologic potency, accidental exposure should be strictly avoided.

Disposal and Environmental Considerations

Dispose of all residues and wastes according to local hazardous waste regulations. Avoid environmental release by using appropriate containment and neutralization techniques.

Regulatory Status

2C-E is regulated as a psychedelic research chemical in many jurisdictions with specific legal controls. Use is restricted to licensed scientific research and experimentation.

Frequently Asked Questions (FAQs)

1. What is the typical dosage for 2C-E in research studies?

• Research doses typically range from 5 to 25 mg, with pellets commonly at 10 mg increments.

2. How long do effects last?

• Effects may last approximately 8 to 12 hours, depending on dosage.

3. What receptors does 2C-E primarily target?

• Serotonin receptors 5-HT2A, 5-HT2B, and 5-HT2C.

4. How does 2C-E differ from 2C-B chemically and pharmacologically?

• 2C-E has an ethyl group instead of bromine at the 4-position, resulting in greater potency and longer duration.

5. What precautions are necessary in handling 2C-E?

• Use PPE, avoid direct contact or inhalation, and handle only in properly ventilated settings.

Conclusion

2C-E 10 MG Pellets are high-purity research compounds providing precise dosing of a potent psychedelic phenethylamine. Their selective serotonin receptor activity makes them valuable tools for neuropharmacological and behavioral research. Safe handling and compliance with legal standards are critical for their use in scientific environments.