2-MMC 250 MG Pellets Product Description

Introduction

2-MMC (2-Methylmethcathinone), also known as ortho-mephedrone, is a synthetic cathinone stimulant and positional isomer of 3-MMC and 4-MMC. It features a methyl group attached to the second (ortho) position on the phenyl ring. Provided as 250 mg pellets, 2-MMC is utilized primarily in scientific research to investigate stimulant pharmacology, structure-activity relationships, and neurochemical effects pertinent to substituted cathinones.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Formula: C11H15NO

• Molecular Weight: 177.24 g/mol

• CAS Number: 1246911-71-6 (base), 1246815-51-9 (hydrochloride salt)

• IUPAC Name: 2-(Methylamino)-1-(2-methylphenyl)propan-1-one

• Synonyms: 2-MMC, 2-Methyl-N-methylcathinone, ortho-mephedrone

Physical Properties and Purity Standards

• Appearance: White or light beige solid compressed pellets containing 250 mg of active compound each.

• Purity: Research-grade purity typically ≥ 98%.

• Solubility: Soluble in dimethylformamide (DMF), dimethyl sulfoxide (DMSO), ethanol, and buffered aqueous solutions at pH 7.2.

• Storage Recommendations: Store in an airtight container away from light, moisture, and heat, preferably refrigerated.

Pharmacological Profile and Mechanism of Action

Proposed Mechanism of Action

2-MMC promotes release and inhibits reuptake of dopamine and norepinephrine neurotransmitters, contributing to its stimulant effects. The ortho-position methyl group likely reduces potency compared to meta- and para- substituted isomers due to steric effects affecting transporter binding affinities. Behavioral effects in models typically manifest within 30-45 minutes with a duration of 2-3 hours.

Research Applications

Primarily used for neuropharmacological studies to examine stimulant mechanisms, transporter interactions, and the metabolic fate of substituted cathinones. Additionally utilized in toxicological and forensic analyses.

Comparative Analysis with Related Compounds

Comparison with Related Compounds

2-MMC differs from 3-MMC and 4-MMC by methyl substitution position, influencing potency and metabolism. It also contrasts with methcathinone in structure and behavioral outcomes, providing unique insights into substituted cathinone pharmacology.

Advantages for Research

The pellet formulation allows for consistent and convenient administration in research. The ortho substitution presents an opportunity to study positional effects on stimulant pharmacology.

Safety and Handling Guidelines

Laboratory Safety

Utilize appropriate PPE including gloves, lab coat, and eye protection. Handle in well-ventilated areas or fume hoods to minimize risk of inhalation or contact.

Disposal and Environmental Considerations

Dispose of in accordance with hazardous chemical waste regulations to prevent environmental harm.

Regulatory Status

2-MMC is regulated in many jurisdictions due to its potential for abuse. It is legally restricted to licensed scientific research.

Frequently Asked Questions (FAQs)

1. What is 2-MMC used for in research?

• To study stimulant pharmacodynamics, neurochemistry, and forensic toxicology.

2. How does 2-MMC differ from other methylmethcathinones?

• The methyl group’s ortho position affects its pharmacology and metabolism.

3. What solvents dissolve 2-MMC?

• DMF, DMSO, ethanol, and buffered aqueous media.

4. How should 2-MMC pellets be stored?

• Airtight, cool, dark, and dry; refrigeration preferred.

5. Is 2-MMC legal to possess?

• Controlled and restricted to authorized research in many locations.

Conclusion

2-MMC 250 MG Pellets provide pure and precisely dosed synthetic cathinone stimulant for research applications. Their unique positional substitution and pellet format facilitate comprehensive studies on stimulant action, metabolism, and related structure-activity relationships under controlled laboratory and regulatory environments.