4-AcO-DPT Fumarate Product Description

Introduction

4-AcO-DPT fumarate is the fumaric acid salt form of 4-Acetoxy-N,N-di-propyltryptamine (4-AcO-DPT), a synthetic psychedelic tryptamine related structurally to psilocybin and psilocin. The fumarate salt enhances its stability and crystallinity for use in precise dosing and research applications. 4-AcO-DPT acts as a prodrug, metabolizing in vivo to the active compound 4-HO-DPT, which interacts primarily with serotonin receptors to produce psychedelic effects.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder or solid.

• Purity: Typically ≥ 97%, confirmed by chromatographic and spectrometric methods.

• Solubility: Soluble in polar solvents like ethanol, methanol, dimethyl sulfoxide (DMSO), and water (salt form).

• Storage: Store in airtight, light-proof containers under cool, dry conditions, preferably refrigerated at -20°C for long-term stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-AcO-DPT fumarate acts primarily as a serotonin 5-HT2A receptor agonist via its active metabolite 4-HO-DPT, inducing psychedelic effects such as perceptual changes, mood enhancement, and introspection. The fumarate salt form offers improved stability and ease of handling in research contexts.

Research Applications

Used in neuropharmacology to study psychedelic tryptamine mechanisms, receptor binding profiles, metabolism, and behavioral effects. The fumarate salt facilitates formulation and analytical consistency in lab settings.

Safety and Handling Guidelines

Handling Safety

Use gloves, lab coat, and eye protection while handling. Work in ventilated laboratory areas or fume hoods to minimize exposure.

Disposal Considerations

Dispose of waste following institutional hazardous materials protocols to prevent environmental contamination.

Regulatory Status

4-AcO-DPT fumarate is regulated as a research chemical in many jurisdictions and is limited to licensed scientific use.

Frequently Asked Questions (FAQs)

1. What is the active metabolite of 4-AcO-DPT?

• 4-Hydroxy-DPT (4-HO-DPT), the active psychedelic compound.

2. What receptors does 4-AcO-DPT affect?

• Primarily serotonin 5-HT2A receptors.

3. What is the typical purity of 4-AcO-DPT fumarate?

• Typically ≥ 97%.

4. How is 4-AcO-DPT fumarate stored?

• In airtight, cool, dark conditions at -20°C.

5. Is 4-AcO-DPT fumarate legal?

• It is restricted to scientific research and controlled in many countries.

Conclusion

4-AcO-DPT fumarate is a high-purity crystalline salt form of the synthetic psychedelic 4-AcO-DPT, used in neuroscience research to explore serotonin-mediated psychedelic effects and metabolic pathways. Its fumarate salt form enhances stability, purity, and ease of use for advanced research applications.