Chem-mist 2F-DCK Spray 30%

PRODUCT DESCRIPTION

Introduction

Chem-mist 2F-DCK Spray 30% is a highly concentrated liquid research chemical formulation containing 2-Fluorodeschloroketamine hydrochloride (2F-DCK HCl), a dissociative arylcyclohexylamine analog of ketamine. Manufactured in an advanced Dutch laboratory, this spray delivers precise sublingual doses with a subtle vanilla aroma for ease of use in research settings. The 20 mL bottle contains 3000 mg of 2F-DCK HCl, with each spray delivering approximately 42 mg of 2F-DCK, designed for superior bioavailability and absorption.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: 2-Fluorodeschloroketamine Hydrochloride

• Molecular Formula: C13H16FNO · HCl

• Molecular Weight: 257.7 g/mol (salt form)

• CAS Number: 111982-49-1

• IUPAC Name: 2-(2-fluorophenyl)-2-(methylamino)cyclohexanone hydrochloride

• Synonyms:

  • 2F-DCK HCl

  • Fluoroketamine hydrochloride

2.2 Physical Properties and Purity Standards

• Appearance: Clear, light yellow 30% liquid solution with vanilla aroma

• Concentration: 30% w/v (300 mg/mL free base equivalent)

• Purity: >98% purity verified by quality control

• Solubility: Fully soluble in water and aqueous solutions with added emulsifiers and solvents (E1520 polyglycol, sodium chloride, etc.)

• Storage Recommendations: Store in amber bottle at 4°C to -20°C to maintain stability and prevent degradation

Pharmacological Profile and Mechanism of Action

3.1 Mechanism of Action

2F-DCK exhibits potent NMDA receptor antagonist activity, creating dissociative effects. The fluorine substitution impacts binding affinity, metabolic stability, and subjective effects, extending the duration compared to ketamine.

3.2 Research Applications

Used for receptor binding studies, pharmacodynamics, behavioral and toxicology research. The spray formulation facilitates precise, repeatable dosing in sublingual or buccal administration studies.

Comparative Analysis with Related Compounds

4.1 Comparison

Compared to ketamine and other arylcyclohexylamines, 2F-DCK displays a modified potency and metabolic profile due to fluorination. The 30% spray is notably more concentrated than common 10% or 20% solutions, suitable for intensive dose-ranging research.

4.2 Advantages

Higher concentration spray enables extended experimental ranges and reduced bottle volume. The formulation’s vanilla aroma, stability, and solubility improve research handling.

Safety and Handling Guidelines

5.1 Handling

Use gloves, eye protection, and lab coat. Operate in a well-ventilated area or fume hood. Avoid skin contact and inhalation of vapors.

5.2 Disposal

Dispose of as controlled chemical waste. Prevent environmental contamination.

5.3 Regulatory Status

2F-DCK is regulated in many countries; verify local legal status before research use.

Frequently Asked Questions (FAQs)

1. What is the concentration of Chem-mist 2F-DCK spray 30%?
   30% w/v (300 mg/mL).

2. How much 2F-DCK is delivered per spray?
   Approximately 42 mg per spray.

3. What solvents and additives are included?
   Aqua, E1520 (polyglycol), vanilla aroma, sodium chloride, food-grade dyes.

4. What effects does 2F-DCK produce?
   Dissociative anesthesia with psychedelic and sedative effects.

5. Is 2F-DCK spray suitable for sublingual use?
   Yes, designed for sublingual and buccal absorption.

Conclusion

Chem-mist 2F-DCK Spray 30% is a high-purity, concentrated research chemical formulation enabling precise dissociative studies with enhanced bioavailability. It meets rigorous quality standards, supporting advanced pharmacological and toxicological research under carefully controlled laboratory conditions.