Chem-mist 2F-DCK Spray 10%

PRODUCT DESCRIPTION

Introduction

Chem-mist 2F-DCK Spray 10% is a liquid formulation of 2-Fluorodeschloroketamine (2F-DCK), a novel arylcyclohexylamine dissociative research chemical structurally related to ketamine. The spray contains a 10% concentration solution of 2F-DCK, designed for facile sublingual or buccal administration allowing precise dosing. This formulation is widely used in research to study dissociative anesthetics, pharmacodynamics, toxicology, and metabolism of novel ketamine analogues.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: 2-Fluorodeschloroketamine

• Molecular Formula: C13H16FNO

• Molecular Weight: 221.27 g/mol

• CAS Number: 111982-50-4

• IUPAC Name: 2-(2-Fluorophenyl)-2-(methylamino)cyclohexan-1-one

• Synonyms:

  • 2F-DCK

  • Fluoroketamine

  • 2-Fluorodeschloroketamine

2.2 Physical Properties and Purity Standards

• Appearance: Clear to slightly yellow liquid solution

• Concentration: 10% w/v (typically 100 mg/mL)

• Purity: ≥98% pharmaceutical-grade purity

• Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, methanol, and aqueous solvent mixtures

• Storage Recommendations: Store in amber glass bottles at 4°C to -20°C, protected from light and moisture to maintain chemical stability

Pharmacological Profile and Mechanism of Action

3.1 Proposed Mechanism of Action

2F-DCK acts as an NMDA receptor antagonist, producing dissociative anesthetic effects similar to ketamine. The fluorine substitution affects binding affinity and metabolism, resulting in prolonged and altered pharmacological profiles compared to ketamine. It is classified pharmacodynamically as a dissociative with sedative, analgesic, and hallucinogenic properties.

3.2 Research Applications

This spray solution is used in neuropharmacology to explore dissociative anesthetic mechanisms, receptor binding studies, behavioral pharmacology, and pharmacokinetic profiling. The spray format offers rapid onset and ease of dose titration in experimental applications.

Comparative Analysis with Related Compounds

4.1 Compare the compound to Compound(s) often compared to

2F-DCK is analogous to ketamine, differing by a fluorine atom substituent replacing chlorine and lacking a chlorine desaturation. It provides a potential longer duration and altered effects compared to ketamine and other halogen-substituted analogs such as 2-Br- or 3-MeO- substituted dissociatives.

4.2 Advantages for Research

The spray formulation allows accurate dosing without the need for complex volumetric measurements. High purity and stability facilitate reproducible results in pharmacodynamics and toxicology experiments.

Safety and Handling Guidelines

5.1 Laboratory Safety

Use proper personal protective equipment including gloves, lab coat, and safety goggles. Handle in a well-ventilated area or fume hood to avoid inhalation of vapors. Avoid skin contact.

5.2 Disposal and Environmental Considerations

Dispose of in accordance with local hazardous waste regulations. Avoid environmental release.

5.3 Regulatory Status

2F-DCK is controlled or regulated in some jurisdictions as a novel psychoactive substance. Confirm legal status before purchase or use.

Frequently Asked Questions (FAQs)

1. What is 2F-DCK?
   An arylcyclohexylamine dissociative structurally related to ketamine.

2. What concentration is in the Chem-mist spray?
   10% w/v or 100 mg/mL solution.

3. What are the main effects of 2F-DCK?
   Dissociative anesthetic, sedative, analgesic with hallucinogenic properties.

4. Is Chem-mist 2F-DCK spray suitable for sublingual use?
   Yes, designed for sublingual or buccal administration.

5. Is 2F-DCK regulated?
   Regulation varies by country; check local laws.

Conclusion

Chem-mist 2F-DCK Spray 10% is a high-purity, ready-to-use solution of a ketamine analog designed for precise dosing in research applications involving dissociative anesthetics. Its formulation supports rapid onset and reproducible study outcomes under regulated, safe laboratory conditions.