DMXE 40mg Pellets (Deoxymethoxetamine) Product Description

Introduction

DMXE 40mg pellets consist of Deoxymethoxetamine, a synthetic arylcyclohexylamine research chemical, formulated in pellet form for controlled laboratory dosing and handling ease. Deoxymethoxetamine, also known as 3′-methyl-2-oxo-PCE or 3D-MXE, is structurally related to methoxetamine (MXE) with a distinct methyl substitution which modifies its pharmacological profile. The pellet formulation provides a stable, solid dosage form suited for precise experimental use, facilitating consistent administration and storage in research settings.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Formula: C15H21NO

• Molecular Weight: 231.33 g/mol

• CAS Number: 2666932-45-0

• IUPAC Name: 2-(ethylamino)-2-(3-methylphenyl)cyclohexan-1-one

• Synonyms: DMXE, 3D-MXE, 3-Me-2′-oxo-PCE

2.2 Physical Properties and Purity Standards

• Appearance: White to off-white pellet form

• Purity: Typically ≥97% (laboratory grade)

• Solubility: Soluble in polar solvents such as ethanol, methanol, moderately soluble in water; pellet form improves handling over powder

• Storage Recommendations: Store pellets in airtight containers, protected from moisture, light, and heat; maintain at room temperature or cooler environments to preserve stability

Pharmacological Profile and Mechanism of Action

3.1 Proposed Mechanism of Action

DMXE exhibits its dissociative effects primarily via antagonism of the N-methyl-D-aspartate (NMDA) receptor, resulting in the modulation of glutamatergic neurotransmission. This interaction leads to altered sensory perception, cognition, and behavior in experimental models. The pellet form facilitates measured, reproducible dosing while maintaining compound integrity.

3.2 Research Applications

Pelleted DMXE is utilized in controlled experimental investigations into NMDA receptor antagonism, neuropharmacology, and psychoactive chemical behavior. The pellet format enhances ease of use in dosing studies, pharmaceutical formulation experiments, and in vitro/in vivo assays requiring consistent, reliable administration protocols.

Comparative Analysis with Related Compounds

4.1 Comparison with Related Compounds

Compared to methoxetamine and other arylcyclohexylamines, DMXE differs by the replacement of the 3-methoxy group with a methyl group, influencing receptor binding affinity and metabolism. The pellet formulation provides practical advantages over freebase or powder forms, improving dosing precision and reducing risks of contamination or degradation during handling.

4.2 Advantages for Research

The 40mg pellet format ensures dosing accuracy and reproducibility, minimizing errors common to powders. Pellets are easier to store and transport while maintaining chemical stability. This formulation facilitates extended experimental design options and consistent administration in pharmacokinetic and pharmacodynamic research.

Safety and Handling Guidelines

5.1 Laboratory Safety

Handle pellets using personal protective equipment including gloves and eye protection. Avoid inhalation of dust or direct skin contact. Use in well-ventilated areas and follow institutional safety procedures.

5.2 Disposal and Environmental Considerations

Dispose of unused pellets and waste in compliance with hazardous chemical protocols. Prevent environmental release by proper containment and disposal.

5.3 Regulatory Status

DMXE pellets are research use only; not approved for human consumption or clinical use. Regulatory control varies by jurisdiction—strict adherence to applicable laws and research institution regulations is required.

Frequently Asked Questions (FAQs)

1. What is the form of DMXE in this product?
   Pellet form, 40mg per pellet, for controlled dosing.

2. What is the molecular weight of DMXE?
   231.33 g/mol.

3. Is DMXE pellet soluble in water?
   Moderately soluble in water; better solubility in polar organic solvents.

4. What research is DMXE pellets used for?
   Studies on NMDA receptor antagonism and neuropharmacology.

5. How should DMXE pellets be stored?
   Store in airtight containers, away from heat, light, and moisture.

Conclusion

DMXE 40mg pellets provide a stable, precise dosage form of Deoxymethoxetamine optimized for laboratory use. This pellet formulation enhances dosing accuracy and experimental repeatability, making it ideal for research into dissociative mechanisms and NMDA receptor pharmacology.