Clonazepam 2mg Rivotril Galenika 30 Tablets

PRODUCT DESCRIPTION

Introduction

Clonazepam 2mg tablets under the brand name Rivotril Galenika are prescription benzodiazepine medications used primarily for the treatment of neurological disorders such as epilepsy, anxiety, panic disorders, and muscle spasms. Manufactured by Galenika, this formulation provides a potent dose of clonazepam in an easy-to-administer tablet form. The standard package contains 30 tablets, each delivering 2 mg of clonazepam.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: Clonazepam

• Chemical Formula: C15H10ClN3O3

• Molecular Weight: 315.7 g/mol

• CAS Number: 1622-61-3

• IUPAC Name: 5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one

• Synonyms:

  • Clonazepam

  • Rivotril

2.2 Physical Properties and Purity Standards

• Appearance: Round, flat tablets, typically green or mint colored

• Dosage Strength: 2 mg per tablet

• Purity: Pharmaceutical-grade, typically ≥98% pure

• Solubility: Slightly soluble in water, soluble in organic solvents

• Storage Recommendations: Store at controlled room temperature (20°C to 25°C), away from moisture and direct light

Pharmacological Profile and Mechanism of Action

3.1 Mechanism of Action

Clonazepam is a high-potency benzodiazepine that acts by enhancing the effect of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor complex. This results in increased chloride ion influx in neurons, leading to neuronal hyperpolarization and decreased excitability, thereby producing anticonvulsant, anxiolytic, muscle-relaxant, and sedative effects.

3.2 Research Applications

Used in comprehensive neuropharmacological studies involving seizure control, anxiety management, and central nervous system depressant mechanisms. The 2 mg dose allows effective titration in pharmacokinetics and dose-response analyses.

Comparative Analysis with Related Compounds

4.1 Compared to Other Benzodiazepines

Clonazepam has a longer half-life and higher potency compared to other benzodiazepines like diazepam. It provides effective seizure suppression and anxiolysis with a wider therapeutic window.

4.2 Advantages for Research

High-purity tablets offer consistent dosing and reliable pharmacological effects. The well-documented clinical profile supports detailed mechanistic and toxicological research.

Safety and Handling Guidelines

5.1 Laboratory Safety

Use gloves, lab coats, and eye protection during handling. Avoid powder inhalation and direct contact to prevent accidental exposure.

5.2 Disposal and Environmental Considerations

Dispose of according to pharmaceutical waste regulations. Avoid environmental contamination.

5.3 Regulatory Status

Clonazepam is classified as a controlled substance worldwide due to its potential for dependence and abuse. Use is strictly regulated and requires prescription.

Frequently Asked Questions (FAQs)

1. What is Clonazepam used for?
   Treatment of epilepsy, panic disorder, anxiety, and muscle spasms.

2. What is the dosage strength of these tablets?
   Each tablet contains 2 mg of clonazepam.

3. How does Clonazepam work?
   Enhances GABAergic activity producing CNS depression.

4. Are Clonazepam tablets safe for long-term use?
   Use under medical supervision; risk of dependence exists.

5. Is Rivotril Galenika regulated?
   Yes, strictly controlled globally.

Conclusion

Clonazepam 2mg Rivotril Galenika Tablets provide a consistent, pharmaceutical-grade benzodiazepine dose essential for neurological disorder management and research into CNS depressant activities. Their stable formulation and standard packaging support both clinical and experimental use under regulatory compliance.