MXiPr (Methoxisopropamine) Product Description

Introduction

MXiPr, short for Methoxisopropamine, also known as Isopropyloxetamine, is an arylcyclohexylamine research chemical related structurally and pharmacologically to dissociatives like ketamine and methoxetamine. It acts as a dissociative anesthetic receptor antagonist and is primarily researched for its NMDA receptor antagonism and anesthetic properties. MXiPr comes commonly in hydrochloride salt form and is used in forensic and neuropharmacological research.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Name: 2-(Isopropylamino)-2-(3-methoxyphenyl)cyclohexan-1-one, monohydrochloride

• Synonyms: Methoxisopropamine, MXiPr, Isopropyloxetamine, 3-methoxy-2-oxo-PCiPr

• Molecular Formula: C16H23NO2 · HCl

• Molecular Weight: 297.8 g/mol (hydrochloride salt)

• CAS Number: Not standardized (research chemical)

Physical and Chemical Properties

• Appearance: White to off-white crystalline powder or solid

• Solubility: 20 mg/mL in DMF and ethanol, 10 mg/mL in DMSO, 2 mg/mL in PBS (pH 7.2)

• Melting Point: Approximately 132-135°C

• Storage: Store at -20°C for optimal stability, protect from moisture and light

Pharmacological Profile and Mechanism of Action

• MXiPr is an NMDA receptor antagonist producing dissociative anesthetic effects similar to ketamine

• It induces neurological dissociation, analgesia, and hallucinations in research models

• Studied for its unique interaction profile distinct from ketamine and methoxetamine

Research Applications

• Neuroscience research focusing on NMDA receptor pharmacology

• Forensic analysis and toxicology

• Studies on dissociative anesthetics and their effects on the central nervous system

Safety and Handling

• Use standard personal protective equipment including gloves, eyewear, and lab coat

• Handle in well-ventilated laboratory environments to avoid inhalation and contact

• Store securely in sealed containers away from heat and moisture

• Dispose of waste according to institutional hazardous material protocols

Regulatory Status

• For research use only; not approved for human consumption or clinical use

• May be regulated as a controlled substance analogue depending on jurisdiction

Frequently Asked Questions (FAQs)

1. What is MXiPr?
   An arylcyclohexylamine dissociative research chemical related to ketamine and methoxetamine.

2. What is its molecular weight?
   Approximately 297.8 g/mol (hydrochloride salt).

3. What receptors does it affect?
   Primarily NMDA receptor antagonist effects.

4. How soluble is MXiPr hydrochloride?
   Soluble in DMF, ethanol, DMSO, and slightly soluble in aqueous buffers.

5. How should it be stored?
   At -20°C, protected from moisture and light.

Conclusion

MXiPr (Methoxisopropamine) is a potent dissociative arylcyclohexylamine research chemical for scientific study of NMDA receptor antagonism and anesthetic properties, requiring strict laboratory handling and regulatory compliance.