DiPT Fumarate (N,N-Diisopropyltryptamine) Product Description

Introduction

DiPT fumarate is a synthetic tryptamine derivative known as N,N-diisopropyltryptamine fumarate salt. This compound is a crystalline solid form of DiPT combined with fumaric acid to increase its stability and solubility for laboratory research. DiPT is a psychedelic-like compound structurally related to other tryptamines, characterized by the substitution of isopropyl groups on the nitrogen atom of the tryptamine core. This fumarate salt form is widely utilized in chemical and pharmacological research involving psychotropic and neuroactive substances.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Formula: C16H24N2·C4H4O4 (DiPT fumarate)

• Molecular Weight: Approximately 388.46 g/mol (salt form)

• CAS Number: 14780-24-6

• IUPAC Name: N-[2-(1H-indol-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine fumarate

• Synonyms: N,N-Diisopropyltryptamine fumarate, DiPT fumarate

2.2 Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder

• Purity: Typically ≥97% by chromatographic analysis

• Solubility: Moderate solubility in water due to fumarate salt form, soluble in ethanol, methanol, and other organic solvents

• Storage Recommendations: Store in airtight containers, protected from moisture and light, preferably at room temperature or in a cool, dry environment

Pharmacological Profile and Mechanism of Action

3.1 Proposed Mechanism of Action

DiPT acts primarily as a serotonergic psychedelic-like compound, interacting with serotonin receptors, notably 5-HT2A receptors, which are implicated in hallucinogenic and psychoactive effects. Its unique isopropyl substitutions modify receptor affinity and activity, making it distinct in its psychoactive profile. As a fumarate salt, it has increased stability and bioavailability in biological research investigations.

3.2 Research Applications

DiPT fumarate is commonly used in neuropharmacological studies for investigating serotonin receptor modulation, psychoactive substance mechanisms, and structure-activity relationships within tryptamine classes. It serves as a chemical tool in psychopharmacology to study the effects of various substitutions on the indole ring and amine groups in hallucinogens and relates to the exploration of potential therapeutic and neuroscientific applications.

Comparative Analysis with Related Compounds

4.1 Comparison with Related Compounds

Compared to other tryptamines such as DMT or DET, DiPT exhibits distinct sensory and receptor interaction profiles due to its bulky isopropyl moieties. The fumarate salt form improves upon the freebase form in ease of handling, solubility, and stability. DiPT’s pharmacological effects differ notably from classic tryptamines by producing auditory distortions and altered sensory perception.

4.2 Advantages for Research

DiPT fumarate’s stable crystalline salt form facilitates precise dosing and reproducible experiment results. Its unique receptor interactions allow research into novel psychoactive profiles and potential receptor subtype selectivity. The fumarate salt enhances water solubility relative to the freebase, supporting in vitro and in vivo bioassays and pharmacokinetic studies.

Safety and Handling Guidelines

5.1 Laboratory Safety

Handle with gloves and eye protection in well-ventilated laboratory settings or a fume hood. Avoid inhalation or direct contact with skin and eyes. Use standard protocols for handling bioactive psychoactive compounds.

5.2 Disposal and Environmental Considerations

Dispose according to hazardous chemical regulations and institutional protocols. Prevent environmental release and avoid contamination of water sources.

5.3 Regulatory Status

DiPT fumarate is classified as a research chemical not intended for human consumption. Its regulatory status varies by country, often restricted or controlled. Compliance with applicable laws and institutional guidelines is mandatory.

Frequently Asked Questions (FAQs)

1. What is the chemical formula of DiPT fumarate?
   C16H24N2·C4H4O4.

2. What is the CAS number for DiPT fumarate?
   14780-24-6.

3. Is DiPT fumarate soluble in water?
   It has moderate water solubility due to the fumarate salt form.

4. What receptor does DiPT mainly affect?
   It primarily affects serotonin receptors, especially 5-HT2A.

5. What are common research uses for DiPT fumarate?
   Researching serotonin receptor activity and psychoactive substance pharmacology.

Conclusion

DiPT fumarate is the fumaric acid salt form of N,N-diisopropyltryptamine, featuring stable crystalline properties and moderate solubility suited for neuropharmacological and psychopharmacological research. With unique receptor interaction profiles, DiPT fumarate is a valuable compound in the study of tryptamine derivatives and psychedelic-related mechanisms.