4B-MAR (4-Bromo-4-methylaminorex) Product Description

Introduction

4B-MAR, or 4-Bromo-4-methylaminorex, is a synthetic stimulant belonging to the substituted aminorex family. It was first definitively identified as a new psychoactive substance in Austria in early 2022. Structurally, it is a brominated derivative of 4-methylaminorex (4-MAR), sharing stimulant properties but with distinct pharmacological and toxicological profiles due to the bromine substitution.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties

• Appearance: White to off-white crystalline powder (typical of substituted aminorex derivatives)

• Purity: Research grade suggested ≥ 99% but specific validated purity data may vary due to emerging status.

• Solubility: Likely soluble in polar organic solvents and possibly aqueous solutions.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4B-MAR, like other aminorex derivatives, is a psychostimulant acting primarily by releasing and inhibiting reuptake of monoamines such as dopamine, norepinephrine, and serotonin, contributing to stimulant and euphoric effects. The bromine substitution may alter potency, duration, and toxicity compared to 4-MAR.

Research Applications

Used mainly in forensic toxicology and research on novel psychoactive substances (NPS). Provided as a research chemical for study on stimulant activity, neurotoxicity, and detection methods.

Safety and Handling Guidelines

Laboratory Safety

Use gloves, lab coat, and eye protection. Handle in ventilated or fume hood environments.

Disposal and Environmental Considerations

Dispose waste per hazardous substance protocols.

Regulatory Status

4B-MAR is an unregulated or newly regulated substance in many countries, controlled by analog or NPS-specific laws, exclusively for research purposes.

Frequently Asked Questions (FAQs)

1. What is 4B-MAR chemically?

• A brominated stimulant of the aminorex family.

2. How does it act?

• Releases and inhibits reuptake of dopamine, norepinephrine, and serotonin.

3. What is its molecular weight?

• Approximately 264.11 g/mol.

4. Is 4B-MAR legal?

• Its regulatory status is emerging; restricted to research in most jurisdictions.

Conclusion

4B-MAR is a high-purity, novel stimulant chemical structurally related to 4-MAR with unique bromine substitution influencing its effects. It is valuable for forensic and neuropharmacological research concerning novel psychoactive stimulant compounds.